Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish

Epilepsy is a chronic brain disorder characterized by recurrent seizures due to abnormal, excessive and synchronous neuronal activities in the brain. It affects approximately 65 million people worldwide, one third of which are still estimated to suffer from refractory seizures. Glutamic acid decarbo...

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Detalles Bibliográficos
Autores principales: Zhang, Yifan, Vanmeert, Michiel, Siekierska, Aleksandra, Ny, Annelii, John, Jubi, Callewaert, Geert, Lescrinier, Eveline, Dehaen, Wim, de Witte, Peter A. M., Kaminski, Rafal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543107/
https://www.ncbi.nlm.nih.gov/pubmed/28775328
http://dx.doi.org/10.1038/s41598-017-06294-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543107/
https://www.ncbi.nlm.nih.gov/pubmed/28775328
http://dx.doi.org/10.1038/s41598-017-06294-w

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