Mucosal vaccination with pili from Group A Streptococcus expressed on Lactococcus lactis generates protective immune responses

The human pathogen Group A Streptococcus (GAS) produces pili that are involved in adhesion and colonisation of the host. These surface-exposed pili are immunogenic and therefore represent an attractive target for vaccine development. The pilus is encoded in the genomic region known as the fibronecti...

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Detalles Bibliográficos
Autores principales: Loh, Jacelyn M. S., Lorenz, Natalie, Tsai, Catherine J.-Y., Khemlani, Adrina Hema J., Proft, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543120/
https://www.ncbi.nlm.nih.gov/pubmed/28775292
http://dx.doi.org/10.1038/s41598-017-07602-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543120/
https://www.ncbi.nlm.nih.gov/pubmed/28775292
http://dx.doi.org/10.1038/s41598-017-07602-0

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