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Mucosal vaccination with pili from Group A Streptococcus expressed on Lactococcus lactis generates protective immune responses
The human pathogen Group A Streptococcus (GAS) produces pili that are involved in adhesion and colonisation of the host. These surface-exposed pili are immunogenic and therefore represent an attractive target for vaccine development. The pilus is encoded in the genomic region known as the fibronecti...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543120/ https://www.ncbi.nlm.nih.gov/pubmed/28775292 http://dx.doi.org/10.1038/s41598-017-07602-0 |