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Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides

Medical means to save the life of human patients affected by drug abuse, envenomation or critical poisoning are currently limited. While the compounds at risks are most often well identified, particularly for bioterrorism, chemical intervention to counteract the toxic effects of the ingested/injecte...

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Detalles Bibliográficos
Autores principales: El-Aziz, Tarek Mohamed Abd, Ravelet, Corinne, Molgo, Jordi, Fiore, Emmanuelle, Pale, Simon, Amar, Muriel, Al-Khoury, Sawsan, Dejeu, Jérôme, Fadl, Mahmoud, Ronjat, Michel, Taiwe, Germain Sotoing, Servent, Denis, Peyrin, Eric, De Waard, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543128/
https://www.ncbi.nlm.nih.gov/pubmed/28775316
http://dx.doi.org/10.1038/s41598-017-07554-5