A polypeptide from the junction region sequence of EWS-FLI1 inhibits Ewing’s sarcoma cells, interacts with the EWS-FLI1 and partner proteins

The EWS-FLI1 chimeric protein uniquely expressed in Ewing’s sarcoma has an obligate role in its aetiology. In our previous report we showed that ectopic expression of the DNA sequences form the junction region (a.a 251–280) can inhibit Ewing’s sarcoma cell growth. In the present report, we introduce...

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Detalles Bibliográficos
Autores principales: Thangaretnam, Krishna Priya, Gopisetty, Gopal, Ramanathan, Priya, Rajkumar, Thangarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543137/
https://www.ncbi.nlm.nih.gov/pubmed/28775288
http://dx.doi.org/10.1038/s41598-017-07482-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543137/
https://www.ncbi.nlm.nih.gov/pubmed/28775288
http://dx.doi.org/10.1038/s41598-017-07482-4

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