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Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation

Microorganisms use carboxylase enzymes to form new carbon-carbon bonds by introducing carbon dioxide gas (CO(2)) or its hydrated form, bicarbonate (HCO(3) (−)), into target molecules. Acetone carboxylases (ACs) catalyze the conversion of substrates acetone and HCO(3) (−) to form the product acetoace...

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Detalles Bibliográficos
Autores principales: Mus, Florence, Eilers, Brian J., Alleman, Alexander B., Kabasakal, Burak V., Wells, Jennifer N., Murray, James W., Nocek, Boguslaw P., DuBois, Jennifer L., Peters, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543143/
https://www.ncbi.nlm.nih.gov/pubmed/28775283
http://dx.doi.org/10.1038/s41598-017-06973-8