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Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation
Microorganisms use carboxylase enzymes to form new carbon-carbon bonds by introducing carbon dioxide gas (CO(2)) or its hydrated form, bicarbonate (HCO(3) (−)), into target molecules. Acetone carboxylases (ACs) catalyze the conversion of substrates acetone and HCO(3) (−) to form the product acetoace...
Autores principales: | Mus, Florence, Eilers, Brian J., Alleman, Alexander B., Kabasakal, Burak V., Wells, Jennifer N., Murray, James W., Nocek, Boguslaw P., DuBois, Jennifer L., Peters, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543143/ https://www.ncbi.nlm.nih.gov/pubmed/28775283 http://dx.doi.org/10.1038/s41598-017-06973-8 |
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