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An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells

During development, pluripotency is a transient state describing a cell’s ability to give rise to all three germ layers and germline. Recent studies have shown that, in vitro, pluripotency is highly dynamic: exogenous stimuli provided to cultures of mouse embryonic stem cells, isolated from pre-impl...

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Detalles Bibliográficos
Autores principales: Godwin, Simon, Ward, Daniel, Pedone, Elisa, Homer, Martin, Fletcher, Alexander G., Marucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543144/
https://www.ncbi.nlm.nih.gov/pubmed/28794899
http://dx.doi.org/10.1038/s41540-017-0020-5