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An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells
During development, pluripotency is a transient state describing a cell’s ability to give rise to all three germ layers and germline. Recent studies have shown that, in vitro, pluripotency is highly dynamic: exogenous stimuli provided to cultures of mouse embryonic stem cells, isolated from pre-impl...
Autores principales: | Godwin, Simon, Ward, Daniel, Pedone, Elisa, Homer, Martin, Fletcher, Alexander G., Marucci, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543144/ https://www.ncbi.nlm.nih.gov/pubmed/28794899 http://dx.doi.org/10.1038/s41540-017-0020-5 |
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