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Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNA(Lys)(UUU) modifications

Efficient protein synthesis in eukaryotes requires diphthamide modification of translation elongation factor eEF2 and wobble uridine modifications of tRNAs. In higher eukaryotes, these processes are important for preventing neurological and developmental defects and cancer. In this study, we used Sc...

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Detalles Bibliográficos
Autores principales: Villahermosa, Desirée, Fleck, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543170/
https://www.ncbi.nlm.nih.gov/pubmed/28775286
http://dx.doi.org/10.1038/s41598-017-07647-1