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Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNA(Lys)(UUU) modifications
Efficient protein synthesis in eukaryotes requires diphthamide modification of translation elongation factor eEF2 and wobble uridine modifications of tRNAs. In higher eukaryotes, these processes are important for preventing neurological and developmental defects and cancer. In this study, we used Sc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543170/ https://www.ncbi.nlm.nih.gov/pubmed/28775286 http://dx.doi.org/10.1038/s41598-017-07647-1 |