Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway

Deoxyarbutin (DeoxyArbutin, dA), a natural compound widely used in skin lighting, displayed selectively cytotoxicity in vitro. In the study, we found that dA significantly inhibited viability/proliferation of B16F10 melanoma cells, induced tumour cell arrest and apoptosis. Furthermore, dA triggered...

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Detalles Bibliográficos
Autores principales: Ma, Limei, Xu, Yao, Wei, Zeliang, Xin, Guang, Xing, Zhihua, Niu, Hai, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543205/
https://www.ncbi.nlm.nih.gov/pubmed/28775302
http://dx.doi.org/10.1038/s41598-017-05416-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543205/
https://www.ncbi.nlm.nih.gov/pubmed/28775302
http://dx.doi.org/10.1038/s41598-017-05416-8

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