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Potassium oxonate induces acute hyperuricemia in the tree shrew (tupaia belangeri chinensis)

Potassium oxonate, a selectively competitive uricase inhibitor, produced hyperuricemia (HUA) in rodents in a previous study. In this study, we employed the tree shrew as an animal model to study potassium oxonate-induced HUA. The effect of allopurinol (ALLO), a uric acid reducer, was also examined i...

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Detalles Bibliográficos
Autores principales: Tang, Dong-Hong, Ye, You-Song, Wang, Chen-Yun, Li, Zhe-Li, Zheng, Hong, Ma, Kai-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543241/
https://www.ncbi.nlm.nih.gov/pubmed/28302963
http://dx.doi.org/10.1538/expanim.16-0096