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The characterization of a full-thickness excision open foot wound model in n5-streptozotocin (STZ)-induced type 2 diabetic rats that mimics diabetic foot ulcer in terms of reduced blood circulation, higher C-reactive protein, elevated inflammation, and reduced cell proliferation

Delayed foot wound healing is a major complication attributed to hyperglycemia in type 2 diabetes mellitus (DM) patients, and these wounds may develop into foot ulcers. There are at least two types of DM wound models used in rodents to study delayed wound healing. However, clinically relevant animal...

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Detalles Bibliográficos
Autores principales: Yu, Caroline Oi-Ling, Leung, Kwok-Sui, Fung, Kwok-Pui, Lam, Francis Fu-Yuen, Ng, Ethel Sau-Kuen, Lau, Kit-Man, Chow, Simon Kwoon-Ho, Cheung, Wing-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543247/
https://www.ncbi.nlm.nih.gov/pubmed/28413186
http://dx.doi.org/10.1538/expanim.17-0016