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Transcription factor SPZ1 promotes TWIST-mediated epithelial–mesenchymal transition and oncogenesis in human liver cancer

The epithelial–mesenchymal transition (EMT) is an important process in the progression of cancer. However, its occurrence and mechanism of regulation are not fully understood. We propose a regulatory pathway in which spermatogenic leucine zipper 1 (SPZ1) promotes EMT through its transactivating abil...

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Detalles Bibliográficos
Autores principales: Wang, L-T, Chiou, S-S, Chai, C-Y, Hsi, E, Chiang, C-M, Huang, S-K, Wang, S-N, Yokoyama, K K, Hsu, S-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543259/
https://www.ncbi.nlm.nih.gov/pubmed/28368406
http://dx.doi.org/10.1038/onc.2017.69