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Integrative network and transcriptomics-based approach predicts genotype- specific drug combinations for melanoma

Computational methods for drug combination predictions are needed to identify effective therapies that improve durability and prevent drug resistance in an efficient manner. In this paper, we present SynGeNet, a computational method that integrates transcriptomics data characterizing disease and dru...

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Detalles Bibliográficos
Autores principales: Regan, Kelly E., Payne, Philip R.O., Li, Fuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543336/
https://www.ncbi.nlm.nih.gov/pubmed/28815138