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Characterizing the Strength of Evidence in FDA Labels for Pharmacogenomic Biomarker-Guided Medication Use

There is great heterogeneity in drug treatment response that is thought to be due to individual-level allelic variation in pharmacogenomic biomarkers. FDA Drug Labels provide information to guide pharmacogenomic biomarker use. Yet, the strength of evidence for clinical validity and clinical utility...

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Detalles Bibliográficos
Autores principales: Chin, Lauren, Devine, Beth, Baradaran, Sarah, Keyloun, Katelyn, Canestaro, William, Pham, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543369/
https://www.ncbi.nlm.nih.gov/pubmed/28815101