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Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition

OBJECTIVES: Rifaximin has clinical benefits in minimal hepatic encephalopathy (MHE) but the mechanism of action is unclear. The antibiotic-dependent and -independent effects of rifaximin need to be elucidated in the setting of MHE-associated microbiota. To assess the action of rifaximin on intestina...

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Detalles Bibliográficos
Autores principales: Kang, Dae J, Kakiyama, Genta, Betrapally, Naga S, Herzog, Jeremy, Nittono, Hiroshi, Hylemon, Phillip B, Zhou, Huiping, Carroll, Ian, Yang, Jing, Gillevet, Patrick M, Jiao, Chunhua, Takei, Hajime, Pandak, William M, Iida, Takashi, Heuman, Douglas M, Fan, Sili, Fiehn, Oliver, Kurosawa, Takao, Sikaroodi, Masoumeh, Sartor, R B, Bajaj, Jasmohan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543406/
https://www.ncbi.nlm.nih.gov/pubmed/27560928
http://dx.doi.org/10.1038/ctg.2016.44