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Locoregional therapy with α‐emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2‐positive gastric cancer in mice

Peritoneal metastasis of gastric cancer (PMGC) is incurable and thus has an extremely poor prognosis. We have found, however, that locoregionally administered trastuzumab armed with astatine‐211 ((211)At‐trastuzumab) is effective against human epidermal growth factor receptor 2 (HER2)‐positive PMGC...

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Detalles Bibliográficos
Autores principales: Li, Huizi Keiko, Morokoshi, Yukie, Nagatsu, Kotaro, Kamada, Tadashi, Hasegawa, Sumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543454/
https://www.ncbi.nlm.nih.gov/pubmed/28514062
http://dx.doi.org/10.1111/cas.13282