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Extracellular histones disarrange vasoactive mediators release through a COX‐NOS interaction in human endothelial cells

Extracellular histones are mediators of inflammation, tissue injury and organ dysfunction. Interactions between circulating histones and vascular endothelial cells are key events in histone‐mediated pathologies. Our aim was to investigate the implication of extracellular histones in the production o...

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Detalles Bibliográficos
Autores principales: Pérez‐Cremades, Daniel, Bueno‐Betí, Carlos, García‐Giménez, José Luis, Ibañez‐Cabellos, José Santiago, Hermenegildo, Carlos, Pallardó, Federico V., Novella, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543457/
https://www.ncbi.nlm.nih.gov/pubmed/28244682
http://dx.doi.org/10.1111/jcmm.13088