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A novel bispecific molecule delivered by recombinant AAV2 suppresses ocular inflammation and choroidal neovascularization

Elevated vascular endothelial growth factor (VEGF) and complement activation are implicated in the pathogenesis of different ocular diseases. The objective of this study was to investigate the hypothesis that dual inhibition of both VEGF and complement activation would confer better protection again...

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Detalles Bibliográficos
Autores principales: Li, Yiming, Zhu, Ping, Verma, Amrisha, Prasad, Tuhina, Deng, Hongxin, Yu, Dechao, Li, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543459/
https://www.ncbi.nlm.nih.gov/pubmed/28332318
http://dx.doi.org/10.1111/jcmm.13086