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Evaluation of high-throughput isomiR identification tools: illuminating the early isomiRome of Tribolium castaneum

BACKGROUND: MicroRNAs carry out post-transcriptional gene regulation in animals by binding to the 3' untranslated regions of mRNAs, causing their degradation or translational repression. MicroRNAs influence many biological functions, and dysregulation can therefore disrupt development or even c...

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Detalles Bibliográficos
Autores principales: Amsel, Daniel, Vilcinskas, Andreas, Billion, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543545/
https://www.ncbi.nlm.nih.gov/pubmed/28774263
http://dx.doi.org/10.1186/s12859-017-1772-z