Evolution of the p53-MDM2 pathway

BACKGROUND: The p53 signalling pathway, which controls cell fate, has been extensively studied due to its prominent role in tumor development. The pathway includes the tumor supressor protein p53, its vertebrate paralogs p63 and p73, and their negative regulators MDM2 and MDM4. The p53/p63/p73-MDM s...

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Detalles Bibliográficos
Autores principales: Åberg, Emma, Saccoccia, Fulvio, Grabherr, Manfred, Ore, Wai Ying Josefin, Jemth, Per, Hultqvist, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543598/
https://www.ncbi.nlm.nih.gov/pubmed/28774266
http://dx.doi.org/10.1186/s12862-017-1023-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543598/
https://www.ncbi.nlm.nih.gov/pubmed/28774266
http://dx.doi.org/10.1186/s12862-017-1023-y

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