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Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis

BACKGROUND: Ferritin plays a central role in the intracellular iron metabolism; the molecule is a nanocage of 24 subunits of the heavy and light types. The heavy subunit (FHC) is provided of a ferroxidase activity and thus performs the key transformation of iron in a non-toxic form. Recently, it has...

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Detalles Bibliográficos
Autores principales: Aversa, I., Zolea, F., Ieranò, C., Bulotta, S., Trotta, A. M., Faniello, M. C., De Marco, C., Malanga, D., Biamonte, F., Viglietto, G., Cuda, G., Scala, S., Costanzo, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543736/
https://www.ncbi.nlm.nih.gov/pubmed/28774348
http://dx.doi.org/10.1186/s13046-017-0571-8