Renal injury is accelerated by global hypoxia-inducible factor 1 alpha deficiency in a mouse model of STZ-induced diabetes

BACKGROUND: Hypoxia inducible factor 1 (HIF-1) activates protective pathways to counteract hypoxia and prevent tissue damage in conjunction with renal injury. The aim of this study was to evaluate a role of HIF-1 in diabetes-induced kidney damage. METHODS: We used a streptozotocin-induced diabetes m...

Descripción completa

Detalles Bibliográficos
Autores principales: Bohuslavova, Romana, Cerychova, Radka, Nepomucka, Katerina, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543752/
https://www.ncbi.nlm.nih.gov/pubmed/28774305
http://dx.doi.org/10.1186/s12902-017-0200-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543752/
https://www.ncbi.nlm.nih.gov/pubmed/28774305
http://dx.doi.org/10.1186/s12902-017-0200-8

Ejemplares similares