Analysis of phosphoinositide 3-kinase inhibitors by bottom-up electron-transfer dissociation hydrogen/deuterium exchange mass spectrometry

Until recently, one of the major limitations of hydrogen/deuterium exchange mass spectrometry (HDX-MS) was the peptide-level resolution afforded by proteolytic digestion. This limitation can be selectively overcome through the use of electron-transfer dissociation to fragment peptides in a manner th...

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Detalles Bibliográficos
Autores principales: Masson, Glenn R., Maslen, Sarah L., Williams, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544108/
https://www.ncbi.nlm.nih.gov/pubmed/28381646
http://dx.doi.org/10.1042/BCJ20170127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544108/
https://www.ncbi.nlm.nih.gov/pubmed/28381646
http://dx.doi.org/10.1042/BCJ20170127

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