GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pleiotropic, Th17-derived cytokine thought to critically contribute to the pathogenesis of diverse autoimmune diseases, including rheumatoid arthritis and psoriasis. Treatment with monoclonal antibodies that block GM-CSF activity is asso...

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Detalles Bibliográficos
Autores principales: Scholz, Tatjana, Weigert, Andreas, Brüne, Bernhard, Sadik, Christian D., Böhm, Beate, Burkhardt, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544216/
https://www.ncbi.nlm.nih.gov/pubmed/28777803
http://dx.doi.org/10.1371/journal.pone.0182646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544216/
https://www.ncbi.nlm.nih.gov/pubmed/28777803
http://dx.doi.org/10.1371/journal.pone.0182646

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