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Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process
Neuropathological studies often use autopsy brain tissue as controls to evaluate changes in protein or RNA levels in several diseases. In mesial temporal lobe epilepsy (MTLE), several genes are up or down regulated throughout the epileptogenic and chronic stages of the disease. Given that postmortem...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544225/ https://www.ncbi.nlm.nih.gov/pubmed/28783762 http://dx.doi.org/10.1371/journal.pone.0182765 |