Infection-stage adjusted dose of beta-lactams for parsimonious and efficient antibiotic treatments: A Pasteurella multocida experimental pneumonia in mice

In this study, the impact of infection stage on clinically and microbiologically efficacious doses and on antibiotic consumption was assessed during a naturally evolving infectious disease, using an original mouse model of pulmonary infection produced by air-borne contamination. When Pasteurella mul...

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Detalles Bibliográficos
Autores principales: Vasseur, Maleck V., Lacroix, Marlene Z., Toutain, Pierre-Louis, Bousquet-Melou, Alain, Ferran, Aude A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544235/
https://www.ncbi.nlm.nih.gov/pubmed/28777819
http://dx.doi.org/10.1371/journal.pone.0182863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544235/
https://www.ncbi.nlm.nih.gov/pubmed/28777819
http://dx.doi.org/10.1371/journal.pone.0182863

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