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4β-Hydroxywithanolide E Modulates Alternative Splicing of Apoptotic Genes in Human Hepatocellular Carcinoma Huh-7 Cells

Alternative splicing is a mechanism for increasing protein diversity from a limited number of genes. Studies have demonstrated that aberrant regulation in the alternative splicing of apoptotic gene transcripts may contribute to the development of cancer. In this study, we isolated 4β-Hydroxywithanol...

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Detalles Bibliográficos
Autores principales: Lee, Chien-Chin, Chang, Wen-Hsin, Chang, Ya-Sian, Liu, Ting-Yuan, Chen, Yu-Chia, Wu, Yang-Chang, Chang, Jan-Gowth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544667/
https://www.ncbi.nlm.nih.gov/pubmed/28779122
http://dx.doi.org/10.1038/s41598-017-07472-6