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4β-Hydroxywithanolide E Modulates Alternative Splicing of Apoptotic Genes in Human Hepatocellular Carcinoma Huh-7 Cells
Alternative splicing is a mechanism for increasing protein diversity from a limited number of genes. Studies have demonstrated that aberrant regulation in the alternative splicing of apoptotic gene transcripts may contribute to the development of cancer. In this study, we isolated 4β-Hydroxywithanol...
Autores principales: | Lee, Chien-Chin, Chang, Wen-Hsin, Chang, Ya-Sian, Liu, Ting-Yuan, Chen, Yu-Chia, Wu, Yang-Chang, Chang, Jan-Gowth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544667/ https://www.ncbi.nlm.nih.gov/pubmed/28779122 http://dx.doi.org/10.1038/s41598-017-07472-6 |
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