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MTHFR gene variants and non-MALT lymphoma development in primary Sjogren’s syndrome

Primary Sjogren’s syndrome (pSS) confers increased risk for non-Hodgkin lymphoma (NHL) development. Two common polymorphisms, the c. 677C > T and c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an enzyme essential in DNA synthesis and methylation, have been associated w...

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Detalles Bibliográficos
Autores principales: Fragkioudaki, Sofia, Nezos, Adrianos, Souliotis, Vassilis L., Chatziandreou, Ilenia, Saetta, Angelica A., Drakoulis, Nikolaos, Tzioufas, Athanasios G., Voulgarelis, Michael, Sfikakis, Petros P., Koutsilieris, Michael, Crow, Mary K., Moutsopoulos, Haralampos M., Mavragani, Clio P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544668/
https://www.ncbi.nlm.nih.gov/pubmed/28779180
http://dx.doi.org/10.1038/s41598-017-07347-w