Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity

In this study, we originally aimed to characterize the potential role of Argonaute 2 (AGO2) in the nucleus, a key protein of the miRNA machinery. We combined Chromatin Immunoprecipitation (ChIP) with high throughput sequencing (ChIP-seq) and quantitative mass spectrometry (ChIP-MS) using the broadly...

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Detalles Bibliográficos
Autores principales: van Eijl, Roderick A. P. M., van den Brand, Teun, Nguyen, Luan N., Mulder, Klaas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544689/
https://www.ncbi.nlm.nih.gov/pubmed/28779093
http://dx.doi.org/10.1038/s41598-017-07539-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544689/
https://www.ncbi.nlm.nih.gov/pubmed/28779093
http://dx.doi.org/10.1038/s41598-017-07539-4

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