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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3

Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...

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Detalles Bibliográficos
Autores principales: Liu, Yanli, Xu, Hanchun, An, Meixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544690/
https://www.ncbi.nlm.nih.gov/pubmed/28779179
http://dx.doi.org/10.1038/s41598-017-07844-y