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mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3
Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proliferation,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544690/ https://www.ncbi.nlm.nih.gov/pubmed/28779179 http://dx.doi.org/10.1038/s41598-017-07844-y |