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Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b

The neurobehavioral effects of paternal smoking and nicotine use have not been widely reported. In the present study, nicotine exposure induced depression in the paternal generation, but reduced depression and promoted hyperactivity in F1 offspring. While this intergenerational effect was not passed...

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Detalles Bibliográficos
Autores principales: Dai, Jingbo, Wang, Zhaoxia, Xu, Wangjie, Zhang, Meixing, Zhu, Zijue, Zhao, Xianglong, Zhang, Dong, Nie, Dongsheng, Wang, Lianyun, Qiao, Zhongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544724/
https://www.ncbi.nlm.nih.gov/pubmed/28779169
http://dx.doi.org/10.1038/s41598-017-07920-3