Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously and regulates actin cytoskeleton remodeling. In order to characterize the role of N-WASP in epidermal homeostasis and cutaneous biology, we generated conditional N-WASP knockout mouse using CK14-cre (cytokeratin 14) to ablate...

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Detalles Bibliográficos
Autores principales: Kalailingam, Pazhanichamy, Tan, Hui Bing, Jain, Neeraj, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544743/
https://www.ncbi.nlm.nih.gov/pubmed/28779153
http://dx.doi.org/10.1038/s41598-017-07125-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544743/
https://www.ncbi.nlm.nih.gov/pubmed/28779153
http://dx.doi.org/10.1038/s41598-017-07125-8

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