Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration

The cell adhesion molecule neuroplastin (Np) is a novel candidate to influence human intelligence. Np-deficient mice display complex cognitive deficits and reduced levels of Plasma Membrane Ca(2+) ATPases (PMCAs), an essential regulator of the intracellular Ca(2+) concentration ([iCa(2+)]) and neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Herrera-Molina, Rodrigo, Mlinac-Jerkovic, Kristina, Ilic, Katarina, Stöber, Franziska, Vemula, Sampath Kumar, Sandoval, Mauricio, Milosevic, Natasa Jovanov, Simic, Goran, Smalla, Karl-Heinz, Goldschmidt, Jürgen, Bognar, Svjetlana Kalanj, Montag, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544750/
https://www.ncbi.nlm.nih.gov/pubmed/28779130
http://dx.doi.org/10.1038/s41598-017-07839-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544750/
https://www.ncbi.nlm.nih.gov/pubmed/28779130
http://dx.doi.org/10.1038/s41598-017-07839-9

Ejemplares similares