In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors

We have previously shown that in vitro transduction with bovine adeno–associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin–deficient mice that are models DFNB1 nonsyndromic hearing loss and deafness. The aims of...

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Detalles Bibliográficos
Autores principales: Crispino, Giulia, Galindo Ramirez, Fabian, Campioni, Matteo, Zorzi, Veronica, Praetorius, Mark, Di Pasquale, Giovanni, Chiorini, John A., Mammano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544751/
https://www.ncbi.nlm.nih.gov/pubmed/28779115
http://dx.doi.org/10.1038/s41598-017-06759-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544751/
https://www.ncbi.nlm.nih.gov/pubmed/28779115
http://dx.doi.org/10.1038/s41598-017-06759-y

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