Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation

Short and long distance cell dispersal can have a marked effect on tumor structure, high cellular motility could lead to faster cell mixing and lower observable intratumor heterogeneity. Here we evaluated a model for cell mixing that investigates how short-range dispersal and cell turnover will acco...

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Detalles Bibliográficos
Autores principales: Pongor, Lőrinc, Harami-Papp, Hajnalka, Méhes, Előd, Czirók, András, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544774/
https://www.ncbi.nlm.nih.gov/pubmed/28779157
http://dx.doi.org/10.1038/s41598-017-07487-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544774/
https://www.ncbi.nlm.nih.gov/pubmed/28779157
http://dx.doi.org/10.1038/s41598-017-07487-z

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