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Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes

BACKGROUND: Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no correlation. Therefore, the multi-faceted role of iron in HIV-1 infection remains en...

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Detalles Bibliográficos
Autores principales: Mancone, Carmine, Grimaldi, Alessio, Refolo, Giulia, Abbate, Isabella, Rozera, Gabriella, Benelli, Dario, Fimia, Gian Maria, Barnaba, Vincenzo, Tripodi, Marco, Piacentini, Mauro, Ciccosanti, Fabiola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545036/
https://www.ncbi.nlm.nih.gov/pubmed/28785172
http://dx.doi.org/10.1186/s12953-017-0126-0