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Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory

Fingolimod (FTY720) was the first per os administered disease-modifying agent approved for the treatment of relapsing–remitting multiple sclerosis. It is thought that fingolimod modulates the immune response by activating sphingosine-1 phosphate receptor type 1 (S1P1) on lymphocytes following its in...

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Detalles Bibliográficos
Autores principales: Efstathopoulos, P, Kourgiantaki, A, Karali, K, Sidiropoulou, K, Margioris, A N, Gravanis, A, Charalampopoulos, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545691/
https://www.ncbi.nlm.nih.gov/pubmed/26795749
http://dx.doi.org/10.1038/tp.2015.179