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Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression
Recent studies implicate the arginine-decarboxylation product agmatine in mood regulation. Agmatine has antidepressant properties in rodent models of depression, and agmatinase (Agmat), the agmatine-degrading enzyme, is upregulated in the brains of mood disorder patients. We have previously shown th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545706/ https://www.ncbi.nlm.nih.gov/pubmed/27404284 http://dx.doi.org/10.1038/tp.2016.116 |