15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

The 15q13.3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13.3 affecting seven genes: FAN1; MTMR10; TRPM1; miR-211; KLF13; OTUD7A; and CHRNA7. The 15q13.3 microdeletion increases the risk of intellectual disability, epilepsy, autism spectrum disorder and schizop...

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Detalles Bibliográficos
Autores principales: Forsingdal, A, Fejgin, K, Nielsen, V, Werge, T, Nielsen, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545711/
https://www.ncbi.nlm.nih.gov/pubmed/27459725
http://dx.doi.org/10.1038/tp.2016.125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545711/
https://www.ncbi.nlm.nih.gov/pubmed/27459725
http://dx.doi.org/10.1038/tp.2016.125

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