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15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes
The 15q13.3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13.3 affecting seven genes: FAN1; MTMR10; TRPM1; miR-211; KLF13; OTUD7A; and CHRNA7. The 15q13.3 microdeletion increases the risk of intellectual disability, epilepsy, autism spectrum disorder and schizop...
Autores principales: | Forsingdal, A, Fejgin, K, Nielsen, V, Werge, T, Nielsen, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545711/ https://www.ncbi.nlm.nih.gov/pubmed/27459725 http://dx.doi.org/10.1038/tp.2016.125 |
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