A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology

It has been proposed that vulnerability to nicotine addiction is moderated by variation at the μ-opioid receptor locus (OPRM1), but results from human studies vary and prospective studies based on genotype are lacking. We have developed a humanized mouse model of the most common functional OPRM1 pol...

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Detalles Bibliográficos
Autores principales: Bernardi, R E, Zohsel, K, Hirth, N, Treutlein, J, Heilig, M, Laucht, M, Spanagel, R, Sommer, W H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545715/
https://www.ncbi.nlm.nih.gov/pubmed/27459726
http://dx.doi.org/10.1038/tp.2016.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545715/
https://www.ncbi.nlm.nih.gov/pubmed/27459726
http://dx.doi.org/10.1038/tp.2016.132

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