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MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls

Variants at microRNA-137 (MIR137), one of the most strongly associated schizophrenia risk loci identified to date, have been associated with poorer cognitive performance. As microRNA-137 is known to regulate the expression of ~1900 other genes, including several that are independently associated wit...

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Detalles Bibliográficos
Autores principales: Cosgrove, D, Harold, D, Mothersill, O, Anney, R, Hill, M J, Bray, N J, Blokland, G, Petryshen, T, Richards, A, Mantripragada, K, Owen, M, O'Donovan, M C, Gill, M, Corvin, A, Morris, D W, Donohoe, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545742/
https://www.ncbi.nlm.nih.gov/pubmed/28117840
http://dx.doi.org/10.1038/tp.2016.286