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Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders
Tic disorders affect ~5% of the population and are frequently comorbid with obsessive-compulsive disorder, autism, and attention deficit disorder. Histamine dysregulation has been identified as a rare genetic cause of tic disorders; mice with a knockout of the histidine decarboxylase (Hdc) gene repr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545743/ https://www.ncbi.nlm.nih.gov/pubmed/28117842 http://dx.doi.org/10.1038/tp.2016.290 |