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Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings

Structural biology of peptides presented by class I and class II MHC proteins has transformed immunology, impacting our understanding of fundamental immune mechanisms and allowing researchers to rationalize immunogenicity and design novel vaccines. However, proteins are not static structures as ofte...

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Detalles Bibliográficos
Autores principales: Ayres, Cory M., Corcelli, Steven A., Baker, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545744/
https://www.ncbi.nlm.nih.gov/pubmed/28824655
http://dx.doi.org/10.3389/fimmu.2017.00935