QbD based approach for optimization of Tenofovir disoproxil fumarate loaded liquid crystal precursor with improved permeability

BCS class III drugs suffer from a drawback of low permeability even though they have high aqueous solubility. The objective of current work was to screen the suitability of glyceryl monooleate (GMO)/Pluronic F127 cubic phase liquid crystals precursors for permeation enhancement and in turn the bioav...

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Detalles Bibliográficos
Autores principales: Patil, Sharvil, Kadam, Chandrashekhar, Pokharkar, Varsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545811/
https://www.ncbi.nlm.nih.gov/pubmed/28794904
http://dx.doi.org/10.1016/j.jare.2017.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545811/
https://www.ncbi.nlm.nih.gov/pubmed/28794904
http://dx.doi.org/10.1016/j.jare.2017.07.005

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