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Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models

Perturbance in inflammatory pathways have been identified as one of the major factors which leads to neurodegenerative diseases (NDD). Owing to the limited access of human brain tissues and the immense complexity of the brain, animal models, specifically mouse models, play a key role in advancing th...

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Detalles Bibliográficos
Autores principales: Kodamullil, Alpha Tom, Iyappan, Anandhi, Karki, Reagon, Madan, Sumit, Younesi, Erfan, Hofmann-Apitius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545904/
https://www.ncbi.nlm.nih.gov/pubmed/28731442
http://dx.doi.org/10.3233/JAD-170255