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Effect of APOE Genotype on Synaptic Proteins in Earlier Adult Life
BACKGROUND: Possession of APOE ɛ4 is a strong risk factor for late-onset Alzheimer’s disease and is associated with loss of synaptic proteins in the elderly even in the absence of Alzheimer’s disease. OBJECTIVE: We hypothesized that ɛ4 allele possession in non-demented adults aged under-75 would als...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545905/ https://www.ncbi.nlm.nih.gov/pubmed/28731446 http://dx.doi.org/10.3233/JAD-170316 |